Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31509052 | 0.90 | CYP1A2 (0.48) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL5050660 | 0.90 | CYP1A2 (0.48) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL20543381 | 0.88 | ALDH1A1 (0.45) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL7904090 | 0.86 | ALDH1A1 (0.50) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL11001271 | 0.86 | ALDH1A1 (0.50) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL11254010 | 0.86 | CYP1A2 (0.48) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL10998499 | 0.85 | CYP1A2 (0.44) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL11001837 | 0.85 | CYP1A2 (0.44) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL28595929 | 0.85 | CYP1A2 (0.44) | CYP1A2CTSLCTSBCTSKALDH1A1 | |
| SCHEMBL11296654 | 0.84 | ALDH1A1 (0.52) | CYP1A2CTSLCTSBCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |