Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9857377 | 0.99 | NR1H4 (0.55) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9713433 | 0.91 | NR1H4 (0.59) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9857436 | 0.91 | NR1H4 (0.65) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9713448 | 0.89 | NR1H4 (0.57) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9713720 | 0.89 | NR1H4 (0.51) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| Hydrochloric Acid SCHEMBL9712766 | 0.88 | NR1H4 (0.50) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9712991 | 0.88 | NR1H4 (0.56) | NR1H4PLA2G4BSCN5ASCN2ACYSLTR1 | |
| SCHEMBL9857424 | 0.88 | NR1H4 (0.56) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H | |
| SCHEMBL9713529 | 0.88 | NR1H4 (0.59) | NR1H4PLA2G4BSCN5ASCN2ACYSLTR1 | |
| SCHEMBL9712985 | 0.88 | NR1H4 (0.56) | NR1H4PLA2G4BSCN5ASCN2ACACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |