Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857436 | 0.94 | NR1H4 (0.65) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9712991 | 0.93 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1SCN5A | |
| SCHEMBL9713448 | 0.92 | NR1H4 (0.57) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9712985 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9857424 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9857064 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9713529 | 0.91 | NR1H4 (0.59) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9713290 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9857010 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9857004 | 0.91 | NR1H4 (0.56) | NR1H4PLA2G4BCYSLTR2CYSLTR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |