Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713007 | 0.90 | KMT2A (0.38) | TP53TSHRKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9713040 | 0.85 | TP53 (0.49) | TP53TSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9712804 | 0.77 | CYP1A2 (0.50) | TP53TSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9713315 | 0.76 | MAPT (0.46) | TP53TSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9712807 | 0.76 | CYP1A2 (0.47) | TP53TSHRMAPTSMN1; SMN2PLK1 | |
| SCHEMBL9713084 | 0.76 | CYP1A2 (0.47) | TP53TSHRMAPTSMN1; SMN2PLK1 | |
| SCHEMBL9712695 | 0.76 | MAPT (0.43) | TP53TSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9713708 | 0.75 | CYP1A2 (0.46) | TP53TSHRMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9713472 | 0.74 | TP53 (0.39) | TP53TSHRMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9713651 | 0.72 | TSHR (0.55) | TP53TSHRMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |