Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712776 | 0.91 | CYP1A2 (0.36) | TP53TSHRMAPK14CNR2CNR1 | |
| SCHEMBL9713027 | 0.90 | PLK1 (0.36) | TP53TSHRMAPTMAPK14CNR2 | |
| SCHEMBL9713040 | 0.89 | TP53 (0.49) | TP53TSHRMAPTMAPK14CNR2 | |
| SCHEMBL9712670 | 0.85 | MAPK14 (0.36) | TP53TSHRMAPTMAPK14CNR2 | |
| SCHEMBL9713007 | 0.85 | KMT2A (0.38) | TP53TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9713537 | 0.84 | MAPT (0.36) | TP53TSHRMAPTMAPK14SMN1; SMN2 | |
| SCHEMBL9713420 | 0.83 | CYP1A2 (0.38) | TP53MAPTMAPK14SMN1; SMN2RAF1 | |
| SCHEMBL9712807 | 0.80 | CYP1A2 (0.47) | TP53TSHRMAPTMAPK14SMN1; SMN2 | |
| SCHEMBL9713231 | 0.79 | TSHR (0.35) | TP53TSHRMAPTNPSR1 | |
| SCHEMBL9713661 | 0.79 | ALDH1A1 (0.40) | TP53TSHRMAPTMAPK14RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |