Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.53 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713298 | 0.89 | SMPD1 (0.60) | PLK1NR1H4MEN1RAB9AKMT2A | |
| SCHEMBL9131621 | 0.88 | PLK1 (0.56) | PLK1CACNA1HCACNA1BACAT1NR1H4 | |
| SCHEMBL9132805 | 0.85 | PLK1 (0.59) | PLK1GAACACNA1HCACNA1BACAT1 | |
| SCHEMBL9129427 | 0.84 | PLK1 (0.61) | PLK1GAACACNA1HCACNA1BACAT1 | |
| SCHEMBL22825227 | 0.82 | PLK1 (0.67) | PLK1GAACACNA1HCACNA1BACAT1 | |
| SCHEMBL9713542 | 0.82 | NR1H4 (0.67) | PLK1NR1H4 | |
| SCHEMBL9132643 | 0.81 | PLK1 (0.55) | PLK1CACNA1HCACNA1BACAT1NR1H4 | |
| SCHEMBL27052314 | 0.81 | PLK1 (0.65) | PLK1GAACACNA1HCACNA1BACAT1 | |
| SCHEMBL9856966 | 0.81 | PLK1 (0.59) | PLK1ACAT1NR1H4RAB9ATSHR | |
| SCHEMBL9713903 | 0.80 | PLK1 (0.74) | PLK1ACAT1NR1H4MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | claimed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | claimed |
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |