Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713566 | 0.92 | NR1H4 (0.52) | NR1H4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL9713751 | 0.89 | NR1H4 (0.58) | NR1H4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL9713633 | 0.88 | NR1H4 (0.56) | NR1H4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL9713622 | 0.87 | NR1H4 (0.58) | NR1H4KMT2AMAPTMEN1TP53 | |
| SCHEMBL9856976 | 0.86 | NR1H4 (0.54) | NR1H4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL9713634 | 0.86 | NR1H4 (0.57) | NR1H4KMT2AMAPTMEN1CYSLTR1 | |
| SCHEMBL9713529 | 0.86 | NR1H4 (0.59) | NR1H4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9857614 | 0.85 | NR1H4 (0.55) | NR1H4KMT2AMAPTMEN1NPC1 | |
| SCHEMBL9857436 | 0.85 | NR1H4 (0.65) | NR1H4KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9713433 | 0.85 | NR1H4 (0.59) | NR1H4KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |