Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 5/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857410 | 0.94 | NR1H4 (0.53) | SLC16A3PLK1NR1H4LTA4HCYSLTR2 | |
| SCHEMBL9857002 | 0.88 | CYSLTR2 (0.59) | SLC16A3PLK1NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9713304 | 0.86 | PLK1 (0.53) | SLC16A3PLK1LTA4HNPC1RAB9A | |
| SCHEMBL9857021 | 0.84 | FFAR1 (0.63) | PLK1NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9856987 | 0.82 | LMNA (0.55) | PLK1NR1H4CYSLTR2CYSLTR1NPC1 | |
| SCHEMBL9713940 | 0.81 | NR1H4 (0.52) | PLK1NR1H4LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL9857625 | 0.81 | NR1H4 (0.52) | PLK1NR1H4LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL9857383 | 0.79 | NR1H4 (0.50) | PLK1NR1H4LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL9857019 | 0.79 | NR1H4 (0.50) | PLK1NR1H4LTA4HCYSLTR2CYSLTR1 | |
| SCHEMBL10746097 | 0.78 | PPARG (0.56) | SLC16A3PLK1NR1H4CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |