SCHEMBL9713414

SCHEMBL9713414

CCCCCCSC1=CC(=O)c2cc(Cl)ccc2C1=O

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 13/20 0.69
S100A4 P26447 6/20 0.60
P4HB P07237 1/20 0.52
G6PD P11413 1/20 0.51
MAP2K7 O14733 1/20 0.40
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
GPR84 Q9NQS5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358334 0.82 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL15732808 0.82 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL15732984 0.82 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL15732931 0.82 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL15732972 0.82 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL10503490 0.81 SOAT1 (0.46) SOAT1S100A4G6PDMAP2K7CDC25A
SCHEMBL15732841 0.80 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL2599427 0.76 SOAT1 (1.00) SOAT1S100A4P4HBG6PDMAP2K7
SCHEMBL9713833 0.75 SOAT1 (0.61) SOAT1S100A4MAP2K7CDC25ACDC25B
SCHEMBL9713336 0.75 PTPN1 (0.40) SOAT1S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091558-A Topical administeration SYNTEX (U.S.A.) INC. (US) 1992-02-25 US disclosed