Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713322 | 0.99 | PTPN1 (0.41) | PTPN1S100A4SOAT1GAAMAPK1 | |
| SCHEMBL9643210 | 0.94 | ALDH1A1 (0.40) | PTPN1S100A4GAAMAPK1RAB9A | |
| SCHEMBL9713511 | 0.90 | S100A4 (0.41) | PTPN1S100A4MAPT | |
| SCHEMBL9629343 | 0.84 | CDC25B (0.51) | PTPN1S100A4GAA | |
| SCHEMBL9713605 | 0.84 | S100A4 (0.38) | PTPN1S100A4 | |
| SCHEMBL11247136 | 0.81 | CDC25B (0.56) | PTPN1S100A4SOAT1 | |
| SCHEMBL9713908 | 0.81 | CDC25B (0.56) | PTPN1S100A4SOAT1 | |
| SCHEMBL9628579 | 0.81 | CDC25B (0.56) | PTPN1S100A4SOAT1 | |
| SCHEMBL9713609 | 0.81 | ALDH1A1 (0.37) | PTPN1S100A4SOAT1MAPK1MAPT | |
| SCHEMBL9643287 | 0.80 | PTPN1 (0.50) | PTPN1S100A4GAAMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |