Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712862 | 0.90 | ALDH1A1 (0.81) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9712738 | 0.88 | ALDH1A1 (0.78) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9713177 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9712712 | 0.86 | ALDH1A1 (0.74) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11105323 | 0.85 | ALDH1A1 (0.73) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11096163 | 0.83 | ALDH1A1 (0.70) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9713159 | 0.82 | TP53 (1.00) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11242366 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9712936 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11257467 | 0.81 | ALDH1A1 (0.67) | ALDH1A1TP53NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |