Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714326 | 0.90 | NR1H4 (0.65) | FFAR1NR1H4S1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL9857414 | 0.87 | NR1H4 (0.59) | FFAR1NR1H4CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL9857383 | 0.85 | NR1H4 (0.50) | FFAR1NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL9857436 | 0.84 | NR1H4 (0.65) | FFAR1NR1H4S1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL9713433 | 0.84 | NR1H4 (0.59) | FFAR1NR1H4S1PR1CYSLTR2CYSLTR1 | |
| SCHEMBL9856976 | 0.83 | NR1H4 (0.54) | FFAR1NR1H4CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL9857010 | 0.83 | NR1H4 (0.56) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9857064 | 0.83 | NR1H4 (0.56) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9857614 | 0.82 | NR1H4 (0.55) | FFAR1NR1H4S1PR1S1PR3S1PR5 | |
| SCHEMBL9713448 | 0.82 | NR1H4 (0.57) | FFAR1NR1H4S1PR1CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | claimed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |