Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CCNC | P24863 | 6/20 | 0.40 |
| ▸ | CDK8 | P49336 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713245 | 0.92 | ABCB11 (0.53) | ABCB11HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9629407 | 0.89 | HTT (0.57) | ABCB11HTTCCNCCDK8KDM4E | |
| SCHEMBL9629306 | 0.85 | ABCB11 (0.68) | ABCB11HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9713667 | 0.83 | ABCB11 (0.65) | ABCB11HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9714251 | 0.82 | HTT (0.48) | ABCB11HTTCCNCCDK8KDM4E | |
| SCHEMBL9628176 | 0.81 | ABCB11 (0.56) | ABCB11HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9713395 | 0.81 | ABCB11 (0.52) | ABCB11HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL9628189 | 0.80 | ABCB11 (0.70) | ABCB11HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL9627666 | 0.80 | GAA (0.56) | ABCB11HTTCCNCCDK8KDM4E | |
| SCHEMBL9627379 | 0.79 | ABCB11 (0.68) | ABCB11HTTKDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |