Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628163 | 0.97 | ABCB11 (0.56) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9629273 | 0.97 | ABCB11 (0.59) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9644133 | 0.92 | ABCB11 (0.70) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9642288 | 0.90 | ABCB11 (0.68) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9642820 | 0.90 | ABCB11 (0.68) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9641979 | 0.86 | ABCB11 (0.81) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9643774 | 0.86 | ABCB11 (0.81) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9629374 | 0.85 | ABCB11 (0.83) | ABCB11KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL9642632 | 0.84 | ABCB11 (0.59) | ABCB11KMT2AKDM4EGLAGAA | |
| SCHEMBL9642650 | 0.84 | ABCB11 (0.59) | ABCB11KMT2AKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |