Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148125 | 0.92 | TSHR (0.58) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL12310326 | 0.92 | TSHR (0.58) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL12310697 | 0.92 | TSHR (0.58) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL12778197 | 0.81 | ALDH1A1 (0.73) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL17152630 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL23514550 | 0.80 | ALDH1A1 (0.63) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL23514419 | 0.80 | ALDH1A1 (0.63) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL12310310 | 0.78 | ALDH1A1 (0.69) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL24322649 | 0.78 | ALDH1A1 (0.69) | ALDH1A1GAALMNAKDM4ETSHR | |
| SCHEMBL3632131 | 0.78 | ALDH1A1 (0.69) | ALDH1A1GAALMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |