Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.58 |
| ▸ | MAOA | P21397 | 14/20 | 0.58 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713957 | 0.82 | MAOB (0.55) | MAOBMAOATOP1PPARGACHE | |
| SCHEMBL9627540 | 0.77 | MAPT (0.49) | TOP1CA12CA1CA7CA9 | |
| SCHEMBL9642788 | 0.77 | MAOB (0.66) | MAOBMAOAPPARGACHECA12 | |
| SCHEMBL9713700 | 0.75 | PDK2 (0.39) | MAOBMAOATOP1PPARGNPC1 | |
| SCHEMBL9627609 | 0.75 | PTPN1 (0.45) | MAOBMAOAACHENPC1RAB9A | |
| SCHEMBL3567336 | 0.74 | PTPN1 (0.62) | MAOBMAOATOP1PPARG | |
| SCHEMBL9714001 | 0.73 | IGLV6-57 (0.45) | — | |
| SCHEMBL9628296 | 0.72 | PTPN1 (0.49) | CA1CA2CA7CA9 | |
| SCHEMBL30003312 | 0.72 | PTPN1 (0.49) | CA1CA2CA7CA9 | |
| SCHEMBL9628330 | 0.70 | TOP1 (0.65) | MAOBMAOATOP1PPARGACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |