Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 13/20 | 0.60 |
| ▸ | MAOA | P21397 | 12/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656273 | 0.89 | PTPN1 (0.57) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL4656058 | 0.82 | MAOB (0.48) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL4656056 | 0.82 | BCHE (0.48) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL30821329 | 0.81 | MAOB (0.55) | PTPN1MAOBMAOAPPARGFFAR1 | |
| SCHEMBL3623732 | 0.80 | PPARG (0.62) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL3623730 | 0.80 | PPARG (0.62) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL3623726 | 0.80 | PPARG (0.62) | PTPN1MAOBMAOAPPARG | |
| SCHEMBL3567958 | 0.77 | PPARG (0.63) | PTPN1MAOBMAOAPPARGFFAR1 | |
| SCHEMBL30821194 | 0.77 | PTPN1 (0.48) | PTPN1MAOBMAOAPPARGTOP1 | |
| SCHEMBL30820954 | 0.74 | MAOB (0.60) | MAOBMAOAPPARGTOP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745439-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-29 | — | — | US | disclosed |
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | JEIL PHARM. CO., LTD. (KR) | 2007-09-27 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
| EP-1740531-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100303-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | PTPN1 2332/4885MAOB 3350/4885MAOA 3544/4885 |
| US-20070225288-A1 | Indene Derivatives and Process for the Preparation Thereof | INSR, GPR119, PPARA | PTPN1 2753/4885MAOB 2721/4885MAOA 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.