Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550587 | 0.84 | LMNA (0.67) | LMNAPKMMAPTALDH1A1CYP19A1 | |
| SCHEMBL6556588 | 0.83 | MEN1 (0.47) | LMNAPKMMAPTALDH1A1CYP19A1 | |
| SCHEMBL10563462 | 0.83 | KDM4E (0.52) | LMNAMAPTCYP19A1MEN1KMT2A | |
| SCHEMBL410471 | 0.82 | LMNA (0.59) | LMNAPKMMAPTALDH1A1CYP19A1 | |
| SCHEMBL10504893 | 0.81 | LMNA (0.52) | LMNAPKMMAPTALDH1A1MEN1 | |
| SCHEMBL10470914 | 0.80 | LMNA (0.46) | LMNAPKMALDH1A1CYP19A1MEN1 | |
| SCHEMBL7893845 | 0.79 | GAA (0.60) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9808626 | 0.78 | CYP19A1 (0.46) | LMNAMAPTCYP19A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9996119 | 0.78 | GAA (0.58) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5066568 | 0.78 | CYP19A1 (0.59) | MAPTALDH1A1CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017474-A1 | TRIAZOLE ANTIFUNGAL AGENTS | PFIZER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |