Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627528 | 0.84 | HTT (0.48) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9643363 | 0.81 | ABCB11 (0.44) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9660612 | 0.81 | HTT (0.52) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9629327 | 0.80 | HTT (0.44) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9714024 | 0.78 | ABCB11 (0.39) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9642605 | 0.78 | ABCB11 (0.42) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9627579 | 0.77 | BACE1 (0.49) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9627465 | 0.76 | HTT (0.69) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9641811 | 0.75 | PDE4A (0.40) | HTTKMT2AALDH1A1MAPTGAA | |
| SCHEMBL9628509 | 0.74 | PTPN1 (0.45) | HTTKMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |