Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809564 | 0.85 | CAPN1 (0.46) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7817120 | 0.76 | CAPN1 (0.44) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7817118 | 0.76 | CAPN1 (0.42) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL8695228 | 0.70 | CAPN1 (0.41) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7809691 | 0.70 | CAPN1 (0.43) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7809628 | 0.69 | KDM4E (0.43) | KDM4EPARP1 | |
| SCHEMBL7809501 | 0.67 | CAPN1 (0.34) | CAPN1KDM4EMEN1KMT2A | |
| SCHEMBL7809688 | 0.67 | CAPN1 (0.40) | CAPN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7810952 | 0.66 | RXFP1 (0.47) | KDM4E | |
| SCHEMBL8061046 | 0.66 | SMN1; SMN2 (0.54) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |