Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714150 | 0.85 | CAPN1 (0.43) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7809628 | 0.83 | KDM4E (0.43) | KDM4EPARP1PADI4 | |
| SCHEMBL7817120 | 0.82 | CAPN1 (0.44) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7810952 | 0.80 | RXFP1 (0.47) | KDM4EPADI4 | |
| SCHEMBL7809688 | 0.80 | CAPN1 (0.40) | CAPN1KDM4EALDH1A1HSD17B10PADI4 | |
| SCHEMBL7809501 | 0.80 | CAPN1 (0.34) | CAPN1KDM4EMEN1KMT2APADI4 | |
| SCHEMBL7816993 | 0.77 | KDM4E (0.41) | KDM4EMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7811182 | 0.76 | KDM4E (0.43) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL7817118 | 0.75 | CAPN1 (0.42) | CAPN1KIF11KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7816823 | 0.75 | KDM4E (0.65) | KDM4ESMN1; SMN2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533882-B1 | 2-QUINOLINONE DERIVATIVES, METHODS FOR PREPARING THE SAME AND FUNGICIDES AND INSECTICIDES INCLUDING THEM | KOREA RES INST CHEM TECH (KR) | 2001-02-07 | — | — | EP | disclosed |
| EP-0533882-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017452-A1 | 2-QUINOLINONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-15 | — | — | WO | disclosed |