Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714327 | 0.91 | ABCB1 (0.75) | ABCB1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL9497589 | 0.90 | ABCB1 (0.65) | ABCB1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL9714285 | 0.88 | ABCB1 (0.58) | ABCB1MAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL10752824 | 0.86 | ABCB1 (0.68) | ABCB1 | |
| SCHEMBL9714124 | 0.83 | ABCB1 (0.64) | ABCB1MAPTPOLBCYP3A4CYP2C9 | |
| SCHEMBL9714597 | 0.82 | ABCB1 (0.76) | ABCB1ALDH1A1POLBCYP3A4CYP2C9 | |
| SCHEMBL10722858 | 0.82 | POLB (0.55) | ABCB1NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL8166763 | 0.82 | POLB (0.74) | ABCB1NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL9652010 | 0.82 | POLB (0.74) | ABCB1NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL9824866 | 0.81 | POLB (0.60) | ABCB1MAPTPOLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |