Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714291 | 0.91 | ABCB1 (0.64) | ABCB1POLBCES2CYP3A4CYP2C9 | |
| SCHEMBL9714320 | 0.88 | ABCB1 (0.66) | ABCB1POLBCYP3A4CYP2C9MEN1 | |
| SCHEMBL10722858 | 0.88 | POLB (0.55) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714635 | 0.87 | POLB (0.63) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714597 | 0.83 | ABCB1 (0.76) | ABCB1POLBCYP3A4CYP2C9MEN1 | |
| SCHEMBL8166763 | 0.83 | POLB (0.74) | ABCB1POLBCES2CYP3A4CYP2C9 | |
| SCHEMBL9652010 | 0.83 | POLB (0.74) | ABCB1POLBCES2CYP3A4CYP2C9 | |
| SCHEMBL9714306 | 0.82 | POLB (0.68) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714095 | 0.82 | POLB (0.56) | ABCB1POLBCYP3A4CYP2C9 | |
| SCHEMBL9714603 | 0.81 | CYP3A4 (0.73) | ABCB1POLBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |