Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714587 | 0.95 | ABCB1 (0.80) | CYP3A4CYP2C9ABCB1POLBNPC1 | |
| SCHEMBL9714143 | 0.95 | ABCB1 (0.83) | CYP3A4CYP2C9ABCB1POLBNPC1 | |
| SCHEMBL9714611 | 0.90 | ABCB1 (0.69) | CYP3A4CYP2C9ABCB1POLBHTT | |
| Hydrochloric Acid SCHEMBL8177261 | 0.89 | ABCB1 (0.68) | CYP3A4CYP2C9ABCB1POLBHTT | |
| SCHEMBL18690328 | 0.89 | ABCB1 (0.91) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL10720059 | 0.87 | CYP3A4 (0.73) | CYP3A4CYP2C9ABCB1POLBHTT | |
| SCHEMBL10722463 | 0.87 | CYP3A4 (0.68) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9714138 | 0.86 | POLB (0.78) | CYP3A4CYP2C9ABCB1POLBHTT | |
| SCHEMBL9714140 | 0.86 | POLB (0.78) | CYP3A4CYP2C9ABCB1POLBHTT | |
| SCHEMBL10722009 | 0.86 | ABCB1 (0.70) | CYP3A4CYP2C9ABCB1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |