Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714138 | 1.00 | POLB (0.78) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714656 | 0.94 | HTT (0.67) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9824849 | 0.89 | POLB (0.78) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9824845 | 0.89 | POLB (0.78) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| Rh-5849 SCHEMBL1538531 | 0.88 | POLB (1.00) | POLBCYP3A4CYP2C9ABCB1HPGD | |
| SCHEMBL9825973 | 0.87 | POLB (0.80) | POLBHTTCYP3A4CYP2C9HPGD | |
| SCHEMBL9825975 | 0.87 | POLB (0.80) | POLBHTTCYP3A4CYP2C9HPGD | |
| SCHEMBL9714589 | 0.86 | CYP3A4 (0.77) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9714587 | 0.86 | ABCB1 (0.80) | POLBHTTCYP3A4CYP2C9ABCB1 | |
| SCHEMBL10719128 | 0.86 | ABCB1 (0.71) | POLBHTTCYP3A4CYP2C9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |