Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312612 | 0.87 | MAPT (0.55) | LMNAAKR1B10AKR1B1NPC1GLA | |
| SCHEMBL312613 | 0.87 | MAPT (0.55) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Propene SCHEMBL28169113 | 0.86 | GLA (0.52) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Chloromethane SCHEMBL27573509 | 0.86 | GLA (0.52) | LMNAAKR1B10AKR1B1NPC1L3MBTL1 | |
| Acetic Acid SCHEMBL28099305 | 0.86 | GLA (0.56) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Acetic Acid SCHEMBL27756791 | 0.86 | GLA (0.56) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Propene SCHEMBL28169115 | 0.86 | GLA (0.52) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Ethylene SCHEMBL28061334 | 0.86 | MAPT (0.53) | LMNAAKR1B10AKR1B1NPC1GLA | |
| Ethylene SCHEMBL28061335 | 0.86 | MAPT (0.53) | LMNAAKR1B10AKR1B1NPC1GLA | |
| SCHEMBL28215687 | 0.84 | GLA (0.55) | LMNAAKR1B10AKR1B1NPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513331-A1 | AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992009554-A1 | AZEOTROPIC ASSISTED TRANSVINYLATION TECHNOLOGY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |