SCHEMBL9714908

SCHEMBL9714908

CCCCc1nc(Cl)c(C(=O)N[C@H](C(=O)O)C(C)CC)n1Cc1ccc2oc(-c3ccccc3-c3nnn[nH]3)c(Br)c2c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.62
AGTR2 P50052 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9695262 1.00 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL9694858 0.94 AGTR1 (0.58) AGTR1
SCHEMBL9694851 0.94 AGTR1 (0.58) AGTR1
SCHEMBL9694931 0.93 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL9695213 0.93 AGTR1 (0.64) AGTR1AGTR2
SCHEMBL9309863 0.92 AGTR1 (0.65) AGTR1AGTR2
SCHEMBL9695183 0.90 AGTR1 (0.62) AGTR1AGTR2
SCHEMBL9309569 0.89 AGTR1 (0.67) AGTR1AGTR2
SCHEMBL9695189 0.89 AGTR1 (0.61) AGTR1AGTR2
SCHEMBL9693707 0.89 AGTR1 (0.61) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992016552-A1 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY GLAXO GROUP LIMITED (GB) 1992-10-01 WO claimed
WO-1992016552-A1 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY GLAXO GROUP LIMITED (GB) 1992-10-01 WO disclosed