Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7221961 | 0.95 | SLC9A1 (0.44) | SLC9A1PKMENPP2MEN1KMT2A | |
| SCHEMBL31459979 | 0.95 | SLC9A1 (0.44) | SLC9A1PKMENPP2MEN1KMT2A | |
| SCHEMBL27337442 | 0.81 | SLC9A1 (0.42) | SLC9A1MEN1KMT2ACA2CA12 | |
| SCHEMBL10391559 | 0.80 | PLAU (0.41) | CYP1A2ENPP2MEN1KMT2ACA2 | |
| SCHEMBL4703026 | 0.78 | SLC9A1 (0.41) | SLC9A1CYP1A2CYP2A6MEN1KMT2A | |
| Alcohol SCHEMBL28071754 | 0.77 | CYP1A2 (0.43) | CYP1A2CYP2A6MEN1KMT2AHSD17B10 | |
| SCHEMBL23530077 | 0.77 | S1PR1 (0.42) | CYP1A2CYP2A6ENPP2MEN1KMT2A | |
| SCHEMBL15352105 | 0.77 | SLC9A1 (0.44) | SLC9A1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL8732557 | 0.77 | SLC9A1 (0.41) | SLC9A1CYP1A2CYP2A6MEN1KMT2A | |
| SCHEMBL12189504 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP2A6ENPP2CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143593-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1992-01-02 | — | — | EP | disclosed |
| US-4736065-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-04-05 | — | — | US | disclosed |
| EP-0143593-A2 | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-06-05 | — | — | EP | disclosed |