Sugi Predict

Sugi Predict / Compounds / SCHEMBL971515

SCHEMBL971515

SCHEMBL971515

O=Cc1cc2ccccc2oc1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 1/20 0.58
▸ HPGD P15428 7/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.56
▸ TYR P14679 1/20 0.56
▸ DAO P14920 1/20 0.56
▸ AKR1B1 P15121 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ KDM4E B2RXH2 7/20 0.53
▸ ALDH1A1 P00352 7/20 0.53
▸ MAOB P27338 6/20 0.53
▸ RAB9A P51151 3/20 0.53
▸ MAPT P10636 2/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ NPSR1 Q6W5P4 1/20 0.53
▸ CA12 O43570 3/20 0.51
▸ CA9 Q16790 3/20 0.51
▸ CA1 P00915 2/20 0.51
▸ CA3 P07451 1/20 0.51
▸ TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494145 1.00 CYP2A6 (0.58) CYP2A6HPGDSMN1; SMN2TYRDAO
Thiophene SCHEMBL16099946 0.90 MAOB (0.49) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL7025703 0.87 MAOB (0.55) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL31678943 0.83 HPGD (0.55) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL15226687 0.83 HPGD (0.59) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL15226969 0.83 SMN1; SMN2 (0.59) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL4121645 0.83 HPGD (0.55) CYP2A6HPGDSMN1; SMN2TYRDAO
Methylpiperazine SCHEMBL28392960 0.83 KDM4E (0.50) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL21949338 0.80 SMN1; SMN2 (0.56) CYP2A6HPGDSMN1; SMN2TYRDAO
SCHEMBL28379349 0.80 HPGD (0.51) CYP2A6HPGDSMN1; SMN2TYRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118876542-A Easily-torn composite packaging material for dairy products 安徽紫金新材料科技股份有限公司 2024-11-01 — — CN claimed
CN-118146209-A 7-Sulfur substituent-chromone-3-formaldehyde compound or derivative thereof, and preparation method and application thereof 中山大学 2024-06-07 — — CN claimed
CN-118084945-A Preparation method and application of coumarin gallium-based carbole derivative 南京林业大学 2024-05-28 — — CN claimed
CN-117865923-A Coumarin formylcarboxylate compounds, methods of preparation and use thereof, and photoinitiator compositions and photocurable compositions containing same 湖北固润科技股份有限公司 2024-04-12 — — CN claimed
CN-115215891-A Trimeric indenyl bridged perylene diimide-coumarin-boron dipyrrole star compound and preparation method thereof 南京林业大学 2022-10-21 — — CN claimed
CN-111116564-B Ratio type fluorescent molecular probe for detecting hypochlorite ions and preparation method and application thereof 江苏大学 2022-04-26 — — CN claimed
CN-114380765-A Preparation and application of 3-allyloxypannine dimer crystal compound 合肥工业大学 2022-04-22 — — CN claimed
CN-113024572-B Spiral-gamma-lactam compound and synthesis method and application thereof 重庆文理学院 2022-03-11 — — CN claimed
CN-109694372-B Two-photon fluorescent probe and preparation method and application thereof 湖南大学 2021-08-24 — — CN claimed
CN-113024572-A Spiral-gamma-lactam compound and synthesis method and application thereof 重庆文理学院 2021-06-25 — — CN claimed
EP-1126833-A2 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2001-08-29 — — EP claimed
US-20010007033-A1 Novel 3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity SUGEN, INC. 2001-07-05 — — US claimed
EP-1054657-A1 AGENT FOR COLORING FIBERS Wella Aktiengesellschaft (DE) 2000-11-29 — — EP claimed
EP-1052261-A1 PYRAN DERIVATIVES AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2000-11-15 — — EP claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 — — WO claimed
WO-2000033799-A1 AGENT FOR COLORING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 2000-06-15 — — WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 — — WO claimed
US-4822790-A ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-18 — — US claimed
US-4684724-A ANTIBIOTICS, BETA-LACTAMASE INHIBITORS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-08-04 — — US claimed
US-4560508-A BETA-LACTAMASE INHIBITORS, ANINICROBIAL AGENT, CHEMICAL INTERMEDIATE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-24 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010007033-A1 Novel 3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity SBK3, MAP4K2, MAP3K20 CYP2A6 2224/4885HPGD 787/4885SMN1; SMN2 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.