Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.49 |
| ▸ | EP300 | Q09472 | 2/20 | 0.49 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.49 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5893158 | 0.99 | BID (0.47) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5893668 | 0.95 | BID (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28155396 | 0.89 | KMO (0.40) | EPHX2 | |
| SCHEMBL27811001 | 0.87 | BID (0.40) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28326505 | 0.85 | CNR1 (0.39) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28456548 | 0.85 | LTB4R2 (0.42) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28142289 | 0.82 | CNR2 (0.41) | BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5680278 | 0.81 | BID (0.40) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28270547 | 0.81 | BID (0.50) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL5678358 | 0.80 | BID (0.38) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213146-B1 | A METHOD FOR THE EXTENSION OF THE TEMPERATURE RANGE FOR THE SMECTIC A PHASE OF A BASE LIQUID CRYSTAL COMPOSITION | MERCK PATENT GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |