SCHEMBL9715359

SCHEMBL9715359

FCC(N=C=S)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 10/20 0.67
TRPA1 O75762 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
HIF1A Q16665 1/20 0.34
CYP2A13 Q16696 1/20 0.34
EPAS1 Q99814 1/20 0.34
CYP2C19 P33261 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
HTR2A P28223 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
NAAA Q02083 3/20 0.31
HRH1 P35367 1/20 0.30
MTOR P42345 1/20 0.30
RAB9A P51151 1/20 0.30
GRM7 Q14831 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3915370 0.80 MIF (1.00) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL6386364 0.78 MIF (0.65) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL331343 0.78 MIF (0.65) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL1526826 0.77 MIF (0.73) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL28071930 0.77 MIF (0.62) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL28071932 0.77 MIF (0.62) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL4594809 0.74 MIF (0.69) MIFALDH1A1NOS3NOS2HTR2A
SCHEMBL2139583 0.74 MIF (0.59) MIFTRPA1ALDH1A1CYP3A4HPGD
SCHEMBL7808 0.73 MIF (0.67) MIFALDH1A1NOS3NOS2HTR2A
SCHEMBL8101646 0.73 MIF (0.57) MIFTRPA1ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308961-B1 THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDE MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-08 EP disclosed