Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808 | 0.95 | MIF (0.67) | MIFALDH1A1KDM4EPOLBNOS3 | |
| SCHEMBL17274465 | 0.93 | MIF (0.65) | MIFALDH1A1KDM4ECNR2SIGMAR1 | |
| SCHEMBL1526826 | 0.89 | MIF (0.73) | MIFALDH1A1KDM4EPOLBNOS3 | |
| SCHEMBL28806778 | 0.83 | MIF (0.46) | MIFALDH1A1KDM4EPOLBNOS3 | |
| SCHEMBL3915370 | 0.82 | MIF (1.00) | MIFALDH1A1POLBNOS3NOS2 | |
| SCHEMBL8101646 | 0.81 | MIF (0.57) | MIFALDH1A1 | |
| SCHEMBL8101546 | 0.79 | MIF (0.54) | MIF | |
| SCHEMBL28071932 | 0.79 | MIF (0.62) | MIFALDH1A1NOS3NOS2HRH1 | |
| SCHEMBL28071930 | 0.79 | MIF (0.62) | MIFALDH1A1NOS3NOS2HRH1 | |
| SCHEMBL920068 | 0.78 | MIF (0.43) | MIFALDH1A1KDM4EPOLBNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466789-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | THE WILLIAM YARBROUGH FOUNDATION (US) | 2025-11-11 | — | — | US | disclosed |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2025-05-22 | — | — | US | disclosed |
| US-20240279169-A9 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2024-08-22 | — | — | US | disclosed |
| US-20230321027-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUNDATION | 2023-10-12 | — | — | US | disclosed |
| US-11654129-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | THE WILLIAM M YARBROUGH FOUNDATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-20230110036-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M YARBROUGH FOUND (US) | 2023-04-13 | — | — | US | disclosed |
| US-20220388954-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | WILLIAM M. YARBROUGH FOUNDATION | 2022-12-08 | — | — | US | disclosed |
| US-11407713-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | THE WILLIAM M. YARBROUGH FOUNDATION (US) | 2022-08-09 | — | — | US | disclosed |
| US-11339125-B2 | Use of isothiocyanate functional surfactants as NRF2 inducers to treat epidermolysis bullosa simplex and related diseases | THE WILLIAM M. YARBROUGH FOUNDATION (US) | 2022-05-24 | — | — | US | disclosed |
| US-11306057-B2 | Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms | THE WILLIAM M. YARBROUGH FOUNDATION (US) | 2022-04-19 | — | — | US | disclosed |
| US-20170065548-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | THE WILLIAM M. YARBROUGH FOUNDATION | 2017-03-09 | — | — | US | disclosed |
| CN-100439332-C | Novel thiourea derivatives and the pharmaceutical compositions containing thd same | PACFIC CORP (KR) | 2008-12-03 | — | — | CN | disclosed |
| EP-1910280-A2 | PROCESS OF SULFONATING 4-AMINOBENZONITRILES | SCHWARZ PHARMA AG (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007009798-A2 | PROCESS OF SULFONATING 4-AMINOBENZONITRILES | SCHWARZ PHARMA AG (DE) | 2007-01-25 | — | — | WO | disclosed |
| CN-1705642-A | Novel N-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO LTD (KR) | 2005-12-07 | — | — | CN | disclosed |
| CN-1418191-A | Novel thiourea derivatives and pharmaceutical compositions containing the same | PACFIC CORP (KR) | 2003-05-14 | — | — | CN | disclosed |
| US-5231209-A | Phenylhexyl isothiocyanate | AMERICAN HEALTH FOUNDATION (US) | 1993-07-27 | — | — | US | disclosed |
| US-5231209-A | Phenylhexyl isothiocyanate | AMERICAN HEALTH FOUNDATION (US) | 1993-07-27 | — | — | US | disclosed |
| US-5114969-A | Method of inhibiting lung tumors, arylalkyl isothiocyanates, and method of synthesizing same | AMERICAN HEALTH FOUNDATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5114969-A | Method of inhibiting lung tumors, arylalkyl isothiocyanates, and method of synthesizing same | AMERICAN HEALTH FOUNDATION (US) | 1992-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230110036-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | F12, MSR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MIF 2036/4885ALDH1A1 1104/4885KDM4E 4382/4885 |
| US-11339125-B2 | Use of isothiocyanate functional surfactants as NRF2 inducers to treat epidermolysis bullosa simplex and related diseases | KEAP1, GSTK1, KRT18 | MIF 4708/4885ALDH1A1 3703/4885KDM4E 4248/4885 |
| US-12466789-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | F12, MSR1, TST | MIF 1902/4885ALDH1A1 1211/4885KDM4E 4446/4885 |
| US-20250161258-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, TMSB10, NHERF1 | MIF 2371/4885ALDH1A1 3056/4885KDM4E 3274/4885 |
| US-20240279169-A9 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | F12, MSR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MIF 2036/4885ALDH1A1 1104/4885KDM4E 4382/4885 |
| US-20220388954-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | F12, MSR1, TST | MIF 1902/4885ALDH1A1 1211/4885KDM4E 4446/4885 |
| US-11654129-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | TST, CFTR, SGMS1 | MIF 2701/4885ALDH1A1 3225/4885KDM4E 4187/4885 |
| US-11306057-B2 | Isothiocyanate functional surfactants, formulations incorporating isothiocyanate functional surfactants and associated methods for treating biofilms | CFTR, TST, CBS | MIF 2105/4885ALDH1A1 2969/4885KDM4E 4206/4885 |
| US-20230321027-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, CFTR, SGMS1 | MIF 2781/4885ALDH1A1 3181/4885KDM4E 4199/4885 |
| US-11407713-B2 | Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use | F12, MSR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MIF 2036/4885ALDH1A1 1104/4885KDM4E 4382/4885 |
| US-20170065548-A1 | ISOTHIOCYANATE FUNCTIONAL SURFACTANTS, FORMULATIONS INCORPORATING THE SAME, AND ASSOCIATED METHODS OF USE | TST, CFTR, SGMS1 | MIF 2701/4885ALDH1A1 3225/4885KDM4E 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.