Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20496905 | 0.78 | KMT2A (0.58) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL9715331 | 0.76 | MEN1 (0.57) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL3302805 | 0.76 | MYC (0.67) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL9715376 | 0.74 | TRPV1 (0.58) | — | |
| SCHEMBL9676641 | 0.74 | PLA2G1B (0.50) | MEN1KMT2AMAPTALDH1A1ALOX12 | |
| SCHEMBL12471200 | 0.74 | TRPV1 (0.48) | MEN1KMT2AMAPTLMNATSHR | |
| SCHEMBL1857910 | 0.74 | TSHR (0.57) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL30486705 | 0.74 | TSHR (0.57) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL29011995 | 0.74 | TSHR (0.57) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL17109772 | 0.73 | TSHR (0.57) | MEN1KMT2AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308961-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0308961-A1 | Thiadiazines, process for production thereof, and insecticide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-03-29 | — | — | EP | disclosed |