SCHEMBL9715376

SCHEMBL9715376

CC(C)(C)c1ccc(CNC(=S)NCC(F)(F)F)cc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715331 0.87 MEN1 (0.57)
SCHEMBL9676641 0.84 PLA2G1B (0.50) TRPV1
SCHEMBL12049602 0.84 PLA2G1B (0.73) TRPV1
SCHEMBL12049334 0.82 ALOX12 (0.72) TRPV1
SCHEMBL12049322 0.82 TRPV1 (0.62) TRPV1
SCHEMBL12060793 0.82 TRPV1 (0.62) TRPV1
SCHEMBL12060869 0.81 TRPV1 (0.61) TRPV1
SCHEMBL4891340 0.81 EPHX2 (0.68) TRPV1
SCHEMBL9427574 0.80 TRPV1 (0.60) TRPV1
SCHEMBL12049605 0.80 TRPV1 (0.58) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0308961-B1 THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDE MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-07-08 EP disclosed
US-5021412-A Protecting agricultural crops MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
EP-0308961-A1 Thiadiazines, process for production thereof, and insecticide MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-03-29 EP disclosed