SCHEMBL9715385

SCHEMBL9715385

C=CC(=O)NCc1nccs1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.42
PSMD14 O00487 1/20 0.41
STAMBP O95630 1/20 0.41
COPS5 Q92905 1/20 0.41
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
NTRK1 P04629 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP2C19 P33261 1/20 0.39
FDPS P14324 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PKM P14618 1/20 0.39
CHRM4 P08173 1/20 0.39
CTSK P43235 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1197194 0.85 RAB9A (0.45) PSMD14STAMBPCOPS5MAPTLMNA
SCHEMBL2936249 0.79 KDM4E (0.46) PSMD14STAMBPCOPS5MAPTLMNA
SCHEMBL1197195 0.78 NTRK1 (0.46) PSMD14STAMBPCOPS5MAPTNTRK1
SCHEMBL2070480 0.77 NPSR1 (0.46) PSMD14STAMBPCOPS5MAPTHTT
SCHEMBL1259666 0.77 POLB (0.47) PSMD14STAMBPCOPS5MAPTNTRK1
SCHEMBL18773805 0.75 RAB9A (0.47) PSMD14STAMBPCOPS5MAPTLMNA
SCHEMBL9368963 0.75 NTRK1 (0.46) PSMD14STAMBPCOPS5MAPTNTRK1
SCHEMBL13870634 0.75 SMN1; SMN2 (0.46) PSMD14STAMBPCOPS5MAPTNTRK1
SCHEMBL4565333 0.74 RAB9A (0.59) MAPTLMNAHTTALDH1A1KDM4E
SCHEMBL16133687 0.73 ADORA2A (0.43) PSMD14STAMBPCOPS5MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164807-B1 MULTIFUNCTIONAL ADDITIVE FOR LUBRIFICATING OILS AND PROCESS FOR THE PREPARATION THEREOF AGIP PETROLI S.p.A. (IT) 1989-10-18 EP claimed
EP-0262502-B1 COMPATIBLE MIXTURES FROM POLYCARBONATE AND METHYLMETHACRYLATE COPOLYMERS RÖHM GMBH (DE) 1992-01-02 EP disclosed
US-4749749-A TRANSPARENT THERMOPLASTIC BLEND; RING-SUBSTITUTED (METH)ACRYLAMIDE MONOMERS ROHM GMBH CHEMISCHE FABRIK (DE) 1988-06-07 US disclosed
EP-0262502-A2 Compatible mixtures from polycarbonate and methylmethacrylate copolymers Röhm GmbH (DE) 1988-04-06 EP disclosed