SCHEMBL9715539

SCHEMBL9715539

COc1ccc(CC(C=O)OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.53
SLC6A4 P31645 1/20 0.52
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
IDO1 P14902 2/20 0.44
CYP2A6 P11509 1/20 0.44
POLB P06746 1/20 0.43
CMA1 P23946 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
AGXT P21549 1/20 0.41
LTA4H P09960 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13843637 0.81 TAAR1 (0.47) SLC6A4CYP1A2CYP2D6CYP2A6PPARG
SCHEMBL8693997 0.81 LDHA (0.56) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL28570428 0.80 LDHA (0.53) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL30290019 0.79 SLC6A4 (0.58) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL9900714 0.79 SLC6A4 (0.58) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL8283115 0.79 SLC6A4 (0.58) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL113550 0.79 SLC6A4 (0.58) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL25381199 0.78 SLC6A4 (0.61) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL1951994 0.78 LDHA (0.53) LDHASLC6A4CYP1A2CYP2D6CYP2C19
SCHEMBL11641396 0.78 TP53 (0.33) LDHATP53TSHRTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5126437-A ALDOPHOSPHAMIDE GLYCOSIDES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL ACTIVE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1992-06-30 US disclosed