Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958771 | 1.00 | CYP1A2 (0.46) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL9715668 | 0.86 | LAP3 (0.47) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL9715672 | 0.86 | CYP1A2 (0.44) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL9715664 | 0.86 | CYP1A2 (0.44) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL962281 | 0.86 | LAP3 (0.47) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL9715674 | 0.86 | CYP1A2 (0.44) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL9715663 | 0.86 | CYP1A2 (0.44) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL14637889 | 0.81 | CYP1A2 (0.50) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL14637890 | 0.81 | CYP1A2 (0.50) | CYP1A2LAP3ANPEPACP3ALPI | |
| SCHEMBL1486794 | 0.81 | ANPEP (0.48) | CYP1A2LAP3ANPEPSLC7A5ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007913-A1 | PEPTIDE ANTAGONISTS OF SH2 BINDING AND THERAPEUTIC USES THEREOF | WARNER-LAMBERT COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |