SCHEMBL9715726

SCHEMBL9715726

CCOC(=O)C1(C=CC=Cc2ccccc2)C=CC=CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
NPC1 O15118 2/20 0.43
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ADORA3 P0DMS8 2/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 1/20 0.39
XBP1 P17861 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
RECQL P46063 1/20 0.38
GAA P10253 1/20 0.37
POLB P06746 1/20 0.37
OPRM1 P35372 3/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715750 0.88 HDAC3 (0.38) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL9715733 0.83 MAOB (0.40) RAB9ASMN1; SMN2LMNANPC1ALDH1A1
SCHEMBL9715739 0.74 MAOB (0.41) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL9715775 0.70 MAOB (0.40) LMNAALDH1A1
SCHEMBL28766223 0.69 CYP3A4 (0.35)
SCHEMBL3685506 0.68 CA12 (0.57) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL3685507 0.68 CA12 (0.57) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL5613524 0.68 CA12 (0.57) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL3685508 0.68 CA12 (0.57) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1
SCHEMBL5020560 0.68 CA12 (0.57) RAB9ASMN1; SMN2LMNAL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311689-B1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-10 EP disclosed
EP-0304495-B1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-05-27 EP disclosed
US-4982007-A CARBONYLATION CATALYST NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-01-01 US disclosed
US-4908473-A Reacting a (1-arylethenyl)vinylbenzene with carbon monoxide and water or alcohol in the presence of carbonylation catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-03-13 US disclosed
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP disclosed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP disclosed