SCHEMBL3685508

SCHEMBL3685508

CCOC(=O)C=C/C=C/c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
RAB9A P51151 4/20 0.55
LMNA P02545 3/20 0.55
NPC1 O15118 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3685507 1.00 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL5613524 1.00 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL5020560 1.00 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL3685506 1.00 CA12 (0.57) CA12CA1CA2CA7CA9
Ethyl Cinnamate SCHEMBL112445 0.88 CA12 (0.72) CA12CA1CA2CA7CA9
Ethyl Cinnamate SCHEMBL112446 0.88 CA12 (0.72) CA12CA1CA2CA7CA9
Ethyl Cinnamate SCHEMBL12001792 0.88 CA12 (0.72) CA12CA1CA2CA7CA9
Ethyl Cinnamate SCHEMBL1866942 0.88 CA12 (0.72) CA12CA1CA2CA7CA9
SCHEMBL14877957 0.87 AKR1B10 (0.55) RAB9ALMNANPC1SMN1; SMN2L3MBTL1
SCHEMBL16213887 0.87 CA12 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683202-B2 Permanent surface modifiers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-23 US disclosed
US-20080249252-A1 New permanent surface modifiers PICCINELLI PIERO 2008-10-09 US disclosed
US-7408077-B2 Permanent surface modifiers CIBA SPECIALTY CHEMICALS CORP. (US) 2008-08-05 US disclosed
US-20040162431-A1 Permanent surface modifiers CIBA SPECIALTY CHEMICALS CORP. 2004-08-19 US disclosed
EP-1373183-A1 PERMANENT SURFACE MODIFIERS Ciba SC Holding AG (CH) 2004-01-02 EP disclosed
WO-2002072530-A1 PERMANENT SURFACE MODIFIERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-09-19 WO disclosed
US-5424164-A Image forming method FUJI PHOTO FILM CO., LTD (JP) 1995-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249252-A1 New permanent surface modifiers SGMS1, SGMS2, PLIN5 CA12 2642/4885CA1 2908/4885CA2 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.