Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.74 |
| ▸ | POLB | P06746 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.63 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10921940 | 0.99 | KMT2A (0.73) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL7335310 | 0.98 | KMT2A (0.71) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL31619825 | 0.93 | KMT2A (0.76) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL9666833 | 0.91 | POLB (0.80) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL31619815 | 0.88 | KMT2A (0.69) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL9666870 | 0.87 | POLB (0.80) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL8126892 | 0.83 | POLB (1.00) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL11076606 | 0.82 | POLB (0.53) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL8147997 | 0.82 | KDM4E (1.00) | KMT2APOLBMEN1KDM4EHSD17B10 | |
| SCHEMBL8136991 | 0.81 | KMT2A (0.85) | KMT2APOLBMEN1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370379-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING LABDANE DITERPENOID DERIVATIVES AND PYRIMIDO(6,1-A) ISOQUINOLIN-4-ONE DERIVATIVES AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-09 | — | — | EP | claimed |
| WO-2025124460-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| CN-120136869-A | Tricyclic fused heterocyclic PDE3/4 dual inhibitor and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-4598148-A | HYPOTENSIVE AGENTS, BRONCHODIALTORS ANTIALLERGENS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-07-01 | — | — | US | disclosed |
| US-4482556-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, ANTIALLERGENS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-11-13 | — | — | US | disclosed |