Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715858 | 0.90 | TP53 (0.43) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL9715856 | 0.86 | TP53 (0.41) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28395002 | 0.84 | TP53 (0.41) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL9715903 | 0.83 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL1270787 | 0.81 | TP53 (0.41) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL28404171 | 0.80 | TP53 (0.39) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL29375309 | 0.80 | TP53 (0.52) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL595016 | 0.80 | TP53 (0.52) | TP53TDP1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL29871077 | 0.79 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL28846228 | 0.79 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |