Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754784 | 0.85 | GABRR1 (0.35) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL14798045 | 0.75 | TSHR (0.41) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL2503574 | 0.75 | TSHR (0.41) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL8765456 | 0.68 | TSHR (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL8765452 | 0.68 | TSHR (0.38) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL8602642 | 0.67 | LMNA (0.35) | LMNATSHRAPEX1CYP1A2 | |
| SCHEMBL3049967 | 0.64 | TSHR (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL3049969 | 0.64 | TSHR (0.43) | GABRR1GABRR2BLMGABRR3LMNA | |
| SCHEMBL6026178 | 0.61 | — | — | |
| SCHEMBL60643 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104641-A | Injecting into blood or joints | M.R.I., INC. (US) | 1992-04-14 | — | — | US | disclosed |
| WO-1991013351-A1 | METHOD FOR ENHANCING NUCLEAR MAGNETIC RESONANCE IMAGING USING A NITROXIDE | M.R.I., INC. (US) | 1991-09-05 | — | — | WO | disclosed |