Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037289 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL31135089 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL10455993 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037400 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL389625 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6037284 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL295988 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL6064426 | 1.00 | TSHR (0.48) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL297100 | 0.98 | TSHR (0.44) | TSHRALDH1A1ABCC4MAPTLMNA | |
| SCHEMBL8610462 | 0.95 | TSHR (0.42) | TSHRALDH1A1ABCC4MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |