Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL7588640 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| Isobutane SCHEMBL11145297 | 0.90 | ALDH1A1 (0.89) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL4627030 | 0.89 | ALDH1A1 (0.76) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL5098181 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL5098171 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL2048901 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| SCHEMBL15617 | 0.88 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| Alcohol SCHEMBL875881 | 0.87 | ALDH1A1 (0.89) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| Ethylene Glycol SCHEMBL27586881 | 0.87 | ALDH1A1 (0.89) | ALDH1A1TSHRCYP3A4TP53CYP2D6 | |
| Ethylene Glycol SCHEMBL27817364 | 0.87 | ALDH1A1 (0.89) | ALDH1A1TSHRCYP3A4TP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106461847-A | Identification medium, method for manufacturing identification medium, and method for using identification medium | 日本瑞翁株式会社 | 2017-02-22 | — | — | CN | disclosed |
| US-5147752-A | Crosslinked binder | FUJI PHOTO FILM CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |