SCHEMBL9715937

SCHEMBL9715937

CC(C)Cc1ccccc1CCc1ccccc1CC(C)C

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.56
GABRB2 P47870 2/20 0.56
SLC6A2 P23975 3/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
TAAR1 Q96RJ0 5/20 0.36
SIGMAR1 Q99720 2/20 0.36
MAOA P21397 1/20 0.36
CYP2A6 P11509 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
AOC3 Q16853 2/20 0.33
SLC18A2 Q05940 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840750 0.92 GABRA1 (0.64) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL5174936 0.89 GABRA1 (0.61) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL5174943 0.89 GABRA1 (0.61) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL6547312 0.89 GABRA1 (0.47) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
Hydrogen Peroxide SCHEMBL5685702 0.86 GABRA1 (0.65) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL8124571 0.86 GABRA1 (0.48) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL10525253 0.86 GABRA1 (0.54) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL11464452 0.84 GABRA1 (0.56) GABRA1GABRB2SLC6A2SLC6A4SLC6A3
SCHEMBL21913441 0.83 TAAR1 (0.55) GABRA1GABRB2SLC6A2TAAR1SIGMAR1
SCHEMBL8128253 0.83 GABRA1 (0.45) GABRA1GABRB2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470651-A1 1,2-Di(4-isobutylphenyl) ethane and its preparation and use as intermediate NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-02-12 EP disclosed
EP-0290050-B1 METHOD FOR PRODUCING ALKYLSTYRENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-08-21 EP disclosed
US-5026939-A Cracking 1,2-di(4-isobutylphenyl)ethane in contact with acid catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-06-25 US disclosed
US-4885419-A IBUPROFEN NIPPON PETROCHEMICALS COMPANY, LTD. (JP) 1989-12-05 US disclosed
EP-0290050-A1 Method for producing alkylstyrene NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed