Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248576 | 1.00 | TSHR (0.33) | TSHRLPAR3LPAR2 | |
| SCHEMBL9228114 | 1.00 | TSHR (0.33) | TSHRLPAR3LPAR2 | |
| Ammonia Solution, Strong SCHEMBL277781 | 0.98 | TSHR (0.32) | TSHR | |
| SCHEMBL4160824 | 0.98 | TSHR (0.30) | TSHR | |
| SCHEMBL977478 | 0.85 | — | — | |
| SCHEMBL15757857 | 0.82 | — | — | |
| SCHEMBL6428871 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL8928273 | 0.76 | DNM1 (0.34) | TSHR | |
| SCHEMBL2902986 | 0.76 | DNM1 (0.34) | TSHR | |
| SCHEMBL1464489 | 0.76 | DNM1 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219720-B1 | SILICONE RELEASE COATINGS CONTAINING HIGHER ALKENYL FUNCTIONAL SILOXANES | DOW CORNING CORPORATION (US) | 1992-03-04 | — | — | EP | disclosed |
| EP-0217334-B1 | RADIATION-CURABLE ORGANOPOLYSILOXANE COATING COMPOSITION | DOW CORNING CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |
| EP-0219720-A2 | Silicone release coatings containing higher alkenyl functional siloxanes | DOW CORNING CORPORATION (US) | 1987-04-29 | — | — | EP | disclosed |
| EP-0217334-A2 | Radiation-curable organopolysiloxane coating composition | DOW CORNING CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4609574-A | METAL-CATALYZED HYDROSILATION | DOW CORNING CORPORATION (US) | 1986-09-02 | — | — | US | disclosed |
| US-4596720-A | Radiation-curable organopolysiloxane coating composition | DOW CORNING CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |