Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716283 | 0.88 | USP2 (0.40) | MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL9716286 | 0.81 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9716337 | 0.80 | USP2 (0.40) | MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL9716311 | 0.79 | USP2 (0.39) | MEN1KMT2ASPHK2SPHK1 | |
| SCHEMBL9716353 | 0.75 | NPC1 (0.36) | MEN1KMT2ASPHK1 | |
| SCHEMBL10551991 | 0.74 | MEN1 (0.49) | MEN1KMT2ASPHK2SPHK1EPHX1 | |
| SCHEMBL5595531 | 0.74 | USP2 (0.42) | MEN1KMT2A | |
| SCHEMBL23292774 | 0.72 | MEN1 (0.49) | MEN1KMT2ASPHK2SPHK1EPHX1 | |
| SCHEMBL23292764 | 0.72 | MEN1 (0.49) | MEN1KMT2ASPHK2SPHK1EPHX1 | |
| SCHEMBL23292756 | 0.72 | MEN1 (0.49) | MEN1KMT2ASPHK2SPHK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |