Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716337 | 0.91 | USP2 (0.40) | USP2HTTPLA2G4BLPAR5MEN1 | |
| SCHEMBL9716311 | 0.90 | USP2 (0.39) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL9716236 | 0.88 | MEN1 (0.34) | MEN1KMT2ASPHK1SPHK2 | |
| SCHEMBL9716353 | 0.86 | NPC1 (0.36) | USP2PLA2G4BMEN1KMT2ASPHK1 | |
| SCHEMBL9716286 | 0.84 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL13996379 | 0.81 | USP2 (0.50) | USP2HTTLPAR5MEN1KMT2A | |
| SCHEMBL14278870 | 0.81 | ALDH1A1 (0.46) | HTTMEN1KMT2ASPHK1SPHK2 | |
| SCHEMBL1626948 | 0.81 | ALDH1A1 (0.46) | HTTMEN1KMT2ASPHK1SPHK2 | |
| SCHEMBL1629698 | 0.81 | ALDH1A1 (0.46) | HTTMEN1KMT2ASPHK1SPHK2 | |
| SCHEMBL9716220 | 0.80 | MEN1 (0.34) | MEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |