Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.30 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716261 | 0.99 | MEN1 (0.40) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9716222 | 0.90 | HTT (0.35) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9716359 | 0.90 | HTT (0.35) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9716340 | 0.89 | MEN1 (0.40) | MEN1KMT2AHTTTHRBMAPT | |
| Hydrochloric Acid SCHEMBL9716322 | 0.88 | PRKD3 (0.44) | MEN1KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL10385452 | 0.86 | MEN1 (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL9720214 | 0.86 | MEN1 (0.54) | MEN1KMT2AHTTTHRBMAPT | |
| Hydrochloric Acid SCHEMBL9716408 | 0.86 | PRKD3 (0.45) | MEN1KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL9716253 | 0.86 | PLA2G2A (0.31) | PLA2G2A | |
| SCHEMBL9716287 | 0.85 | MEN1 (0.41) | MEN1KMT2AUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |