Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.55 |
| ▸ | PRKCG | P05129 | 2/20 | 0.55 |
| ▸ | PRKCB | P05771 | 2/20 | 0.55 |
| ▸ | PRKCA | P17252 | 2/20 | 0.55 |
| ▸ | PRKCH | P24723 | 2/20 | 0.55 |
| ▸ | PRKCI | P41743 | 2/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.54 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.54 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.54 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.54 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550605 | 1.00 | PRKD3 (0.55) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10551115 | 0.87 | PRKD3 (0.49) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL16475728 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL17184093 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL102381 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL11299536 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL11299532 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL11299539 | 0.87 | LPAR1 (0.56) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL8912777 | 0.85 | LPAR1 (0.48) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4401638 | 0.84 | PRKD3 (0.72) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103007-A | Antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0378763-A1 | Lipids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-25 | — | — | EP | disclosed |
| US-4845219-A | ANTITUMOR, ANTOCOAGULANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0255366-A2 | Nitrogen- and sulfur-containing lipid compound, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-02-03 | — | — | EP | disclosed |